ZETIA – Everything you wanted to know about it

ZETIA is used along with a low cholesterol/ low-fat diet and exercise to help lower cholesterol in the blood. It is prescribed for patients who cannot control their cholesterol levels with the help of diet and exercise. Let’s get to know how it works, it’s uses, side effects, precautions to take care.

The drug can be given alone or with other drugs (such as “statins” or fibrates). This drug acts by reducing the amount of cholesterol your body absorbs from your diet. Lowering cholesterol levels in the body may help to prevent stroke and heart attack. The drug should avoid in clients with moderate to severe liver disease. ZETIA drug has been approved in 2002 by FDA.

ZETIA composition and active ingredients

ZETIA is available as an oral tablet containing 10 mg of ezetimibe as an active ingredient. ZETIA also contains following inactive ingredients:

  • Croscarmellose sodium NF
  • Lactose monohydrate NF
  • Magnesium stearate NF
  • Microcrystalline cellulose NF
  • Movidone USP
  • Sodium lauryl sulfate NF

How do ZETIA works?

ZETIA (ezetimibe) is a drug used to treat high cholesterol that works differently than statins, which lower cholesterol by 35 to 60% in most patients and reduce the risk of heart attack. Statins work by blocking an enzyme used by the liver to produce cholesterol.

The drug acts on the brush border of the small intestine and inhibits the absorption of cholesterol. This leads to a decrease in the delivery of intestinal cholesterol to the liver. But other medicines of cholesterol should not be taken together, and you need a frequent blood test to measure your cholesterol levels.

ZETIA uses and benefits

ZETIA (ezetimibe) is used in treatment for the following conditions:

  • Hypercholesterolemia
  • Hyperlipoproteinemia
  • Hypertriglyceridemia
  • Atherosclerosis
  • Myocardial infarction prophylaxis
  • Coronary artery disease prevention after a heart transplant
  • Stroke prophylaxis

Side effects of ZETIA

When some drug is used to treating some health conditions, along with its intended benefits there might be some possible side effects too. The listed side effects may not be the same in every individual. But if they persist take time for its cure, do consult your physician for immediate medical attention.

Below mentioned are some possible side effects of the use of ZETIA are, There may be other side effects too that are not mentioned here. Consult your physician for proper guidance before using this drug to avoid adverse side effects.

  • Pancreatitis
  • Muscular weakness
  • Chest pain
  • Dizziness
  • Headache
  • Diarrhea
  • Cough
  • Mild stomach pain

The recommended dose of ZETIA is 10 mg once daily. The drug can be consumed with or without food. Tell your physician all drugs and supplements you use. Inform the physician about plans pregnancy, because it is unknown, it may harm the fetus or if the drug ZETIA passes into breast milk, it could harm a nursing baby. Consult your physician before breastfeeding.

Precautions before using ZETIA

ZETIA, before you consume, inform your physician if you are under any other medications, or using any over the counter products like supplements, herbal products, etc. History of allergies, diseases, and also about your current health conditions, for eg; pregnancy, plan of surgery, etc. Inform your Physician about your health problems if any to avoid side effects. The dose of this medicine should be strictly followed as directed by your physician or follow the directions printed on the product insert. Dosage is based on your condition and symptoms. Let your physician know if the problem never hinders and continues for a long time or increases.


Taking more than prescribed ZETIA may cause harmful side effects. Consult your physician if you find any side effects. Read the label carefully before taking this medicine to avoid Overdosage.  An excess dose can result in confusion, dizziness, headache, fatigue, sedation.

Missing dosage

If you have missed a single dose, then take it soon as possible, and if it’s near time for next dose, then skip the missed dose and continue the regular dosage schedule. Don’t take an extra dose.

ZETIA Drug Interactions

If your taking two or more different drugs together there is a chance of medicine interaction, resulting in adverse effects.

If you use other over the counter products or other drugs at the same time, the effects of the ZETIA may change. In such case, the risk of getting side effects might be higher or the effectiveness of the drug may impact. Intimate your doctor about your medical history, a list of drugs taken by you, then it is easy to prevent or manage drug interactions. ZETIA may interact with the following medicines and products such as:

  • Colestipol
  • Cholestyramine
  • Gemfibrozil
  • Colesevelam
  • Cyclosporine
  • Blood thinners

Available medicines of ZETIA

Below mentioned are a few examples of medicines with the ZETIA as their key ingredient. This is not a comprehensive list. This list is for informative purpose only. It is advised to use this medicine with proper advice from your physician.

  • Crestor (rosuvastatin)
  • Lipitor (atorvastatin)

If for some reason an experienced doctor is not available around you, then you can contact us here.


ZETIA - Everything you wanted to know about it
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