Table of Contents

  1. What is Temozolomide?
  2. Constituents
  3. Indications
  4. How does Temozolomide work?
  5. How to Take Temozolomide?
  6. Common Dosage for Temozolomide?
  7. When to Avoid Temozolomide?
  8. Side-effects of Temozolomide?
  9. Effects on organs?
  10. Reported Allergic Reactions?
  11. Effect on menstrual cycle
  12. Drug Interactions To Be Careful About
  13. Food interactions (if any)
  14. Interactions with laboratory procedures
  15. Shows Effects / Results In and how long does the effect stay:
  16. Is Temozolomide Addictive?
  17. Can I have Temozolomide with alcohol?
  18. Can I have Temozolomide When Pregnant?
  19. Can I have Temozolomide when feeding a baby?
  20. Can I drive after taking Temozolomide?
  21. Effect of overdose of Temozolomide?
  22. Effect of using expired Temozolomide?
  23. Effect of missing a dose of Temozolomide?
  24. Storage requirements

What Is Temozolomide?

A basic introduction in brief

Temozolomide is an FDA-approved drug. Temozolomide is an anti-cancer drug that is used for the treatment of brain cancer.

Type of drug

It is a type of anti-cancer chemotherapeutic drug which is used for the treatment of brain tumors.

Use in brief

Temozolomide drug is used for the treatment of brain cancer in adults.

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This drug contains 5mg, 20mg, 100mg, 140mg, 180mg, and 250mg of Temozolomide along with other inactive excipients.


Refractory anaplastic astrocytoma: Temozolomide drug is indicated for the treatment of refractory anaplastic astrocytoma in adults.

Newly diagnosed glioblastoma multiforme: This drug is indicating as a maintenance treatment for the treatment of newly diagnosed glioblastoma multiforme.

How Does Temozolomide Work?

Temozolomide is a drug which enters the brain and damage genetic framework of tumor cell.

Read more about lung camcer medications

How to Take Temozolomide?

Form of Medicine

Temozolomide is a drug that is available in the form of a capsule. The capsule of temozolomide is available in various strengths such as 5mg, 20mg, 100mg, 140mg, 180mg and 250mg.

When to Use

Your doctor prescribes this drug when you are suffering from brain tumors.

How to Use

Take this tablet before one hour of meal. Swallow the whole tablet and do not try to chew and crush this tablet. For best result take advice from your doctor. If you feel vomit after taking this drug then do not take other medication and wait for the scheduled time of the next regular dose.

Common Dosage for Temozolomide

The dosage of this drug is decided based on weight, height, medical condition and response of treatment in patients. For best and effective results, follow the instruction of your doctors for taking his medicine.

When to Avoid Temozolomide?

Avoid intake of this tablet if any symptoms are developed related to the condition such as:

  • Opportunistic infections
  • Hypersensitivity

Side-Effects of Temozolomide

The common side effects of temozolomide are listed below such as:

  • Memory loss
  • Convulsion
  • Insomnia
  • Weakness
  • Diarrhea
  • Dizziness
  • Rashes
  • Vomiting
  • Hair loss
  • Fever
  • Coordination disorders
  • Constipation
  • Viral infection

Effects on Organs

Some effects of this drug on body organs such as

  • Decrease bone marrow functions
  • Blood cells disorders

Reported Allergic Reactions?

Do not use this drug if you have any allergic reaction from the temozolomide drug and its constituents.

Effect on Menstrual Cycle

The effect of this drug on the menstrual cycle is still unknown. Take information from your doctor about the effect of this drug on the menstrual cycle.

Drug Interactions to Be Careful About

Some drugs interact with this drug and change their mode of action in the body such as:

  • Amlodipine
  • Furosemide
  • Lisinopril
  • Keppra
  • Omeprazole
  • Lorazepam

Food Interactions

Take this tablet 1 hour before meal because food can reduce the rate and extent of absorption of this drug in the body.

Interactions with Laboratory Procedures

The information about the interaction of this drug with laboratory procedure is still unavailable.

Shows Effects / Results In and How Long Do the Effect Stay

The half-life of this drug is approximately is 1.8 hours. Most chemotherapeutic drugs stay in the body for a few hours or a day.

Is Temozolomide Addictive?

This drug does not show any additive effect but does not use this drug for a long time because this can cause some serious side effects.

Can I Have Temozolomide With Alcohol?

Avoid consumption of alcohol with temozolomide.  Drinking alcohol may interact with the efficacy of this drug and may also lead to unwanted side effects.

Can I Have Temozolomide When Pregnant?

Avoid taking this drug during pregnancy. Temozolomide may take some harmful effects on the fetus.

Can I Have Temozolomide When Feeding A Baby?

Do not use this drug during breastfeeding. This drug can cause some possible risk in infants.

Can I Drive After Taking Temozolomide?

Do not drive and operate the machine after taking this medicine. The administration of a temozolomide tablet makes you tired and sleepy. Drive only when you feel that you can drive safely.

Effect of Overdose of Temozolomide

Do not take an overdose and a double dose of this drug. If you have taken an overdose of this drug by mistake, immediately call your doctor and take emergency treatment.

Effect of Using Expired Temozolomide

Do not use expired temozolomide drug because after expiry date temozolomide drug may have reduced therapeutic efficacy and also cause some unwanted and toxic effects.

Effect of Missing a Dose of Temozolomide

You should take every dose on its schedule time. When you missed your regular dose then avoid that dose and take the next regular dose at their schedule time. Do not take a double dose to make up for the missed dose. In case you have taken a double dose, immediately consult with your healthcare provider.

Storage Requirements

Store the drug at room temperature. Keep away this drug from light and moisture.

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