Signoflam – Composition, Uses, Side-Effects, Substitutes, Warnings

Signoflam Tablet is a painkiller (a non-steroidal anti-inflammatory drug), prescribed to treat fever, headache, muscle pain, toothache, sore throat,  and rheumatic conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Get to know how Signoflam works, its side effects, precautions, and contraindications where Signoflam is not suggested.

Read about Signoflam in Hindi

Signoflam Tablet composition and active ingredients

Signoflam contains below mentioned as active ingredients:

Manufactured & marketed byLupin Pharmaceutical Limited.
Prescription – Required
Form – Available in Tablets and Topical Gel forms
Drug type – As this medicine contains 3 different ingredients, it works as an NSAID, Analgesic, and Antipyretic medicine.

Signoflam tablet Uses

Signoflam tablet is an analgesic & antipyretic medicine used to control, prevention & improvement of the following diseases, conditions, and symptoms:


Osteoarthritis commonly occurs in patients over the age of 50 and causes the loss of the cartilage and bone tissue which causes severe joint pain. Signoflam is used to treat the pain caused by Osteoarthritis.

Learn about Knee Brace for Osteoarthritis

Rheumatoid arthritis

Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation of the joints. In this condition, Signoflam tablet is used to treat symptoms like swelling, pain, and stiffness of joints associated with it.

Menstrual pain

Signoflam tablet is used in the treatment of menstrual cramps and lower abdominal pains felt before and during menstruation.

Ankylosing spondylitis

Spinal arthritis can lead to the fusion of the vertebrae. In this condition, Signoflam tablet is used to treat symptoms like stiffness and pain associated with it.

Back pain

Signoflam tablet is also used to treat mild to severe back pain caused by arthritis, sciatica, herniated disc.

Frozen shoulder

Frozen shoulder is a common orthopedic ailment characterized by stiffness and pain in the shoulder joint. Signoflam tablet is used to treat symptoms like stiffness and pain associated with frozen shoulder.


Gout is a type of arthritis characterized by severe pain, tenderness, and redness in the joints. Signoflam tablet is used to treat symptoms like joint pain and tenderness in this condition.

How does Signoflam tablet work?

To understand the mechanism of action of Signoflam let’s get to know how each of the ingredients in it works.

Aceclofenac belongs to a class of medicines called NSAID’s (non-steroidal anti-inflammatory drugs). It reduces the production of a chemical called prostaglandins. This chemical causes swelling and pain in the body. The drug blocks the production and action of prostaglandins and relives the body pain and swelling.

Serratiopeptidase is a Proteolytic enzyme (inhibitor). It works by reducing the pain and inflammation generator system by disrupting the mediator chemicals; thereby it reduces the inflammation and pain.

Paracetamol is an antipyretic and analgesic drug. It works by stimulating the brain’s temperature-regulating region and increasing the pain threshold and increases the blood flow to the skin. It results in sweating, heat loss and helps in lowering the body temperature or fever.

How to Use Signoflam tablet

  • Signoflam tablet is available in tablet form and is used through oral route.
  • Never crush, break or chew the tablet, but use the whole tablet at once with some water or any liquids.
  • Follow regular dosage schedules as prescribed by the doctor and complete the full course of the dosage as directed by the doctor.
  • Read carefully the instruction mentioned on the medicine leaflet to understand the instructions.

Signoflam tablet Side Effects

Below are the common side effects that can occur from Signoflam tablet. Some of the side effects may occur very rarely. If you experience any of these side effects, inform your doctor immediately:

  • Abdominal pain
  • Allergy
  • Drowsiness
  • Swollen facial features
  • Nausea and vomiting
  • Shortness of breath
  • Feeling of sickness

Signoflam Tablet – Contraindications

Signoflam Tablet should not be taken if you have the following ailments:

  • Allergy to Aceclofenac
  • Active peptic ulcer
  • Asthma
  • Bleeding disorders
  • Acute rhinitis
  • Blood coagulation disorders

Signoflam tablet Dosage

The dosage of this medicine varies with the patient’s age and the condition for which it is being administered. For example, the typical dosage for adults is one tablet, two times a day. Please consult with your doctor to know about the correct dosage for the speedy recovery.

Precautions while taking Signoflam tablet

  • Use this medicine only if prescribed by the doctor
  • Do not take Signoflam tablet if you are allergic to Aceclofenac or Paracetamol
  • Tell your doctor if you are taking any other medicine
  • Tell your doctor if you are suffering from any disease
  • If you experience drowsiness, dizziness after using this medicine, you must not drive or use heavy machinery that requires alertness
  • Tell your doctor all the medicines you are using for heart, kidney, asthma and gastric problems before he prescribes Signoflam tablet for your condition
  • Do not take this medicine after the expiry date stated on the carton package
  • Swallow the tablet whole with a glass of water do not crush or chew the tablets
  • This medicine is not safe to take if you are pregnant or planning to get pregnant
  • Signoflam tablet is not safe to take if you are breastfeeding or planning to start breastfeeding. Consult your doctor before taking this drug.
  • This medicine should not be given to infants.

Signoflam Tablet – Drug Interactions

If you use other over the counter products or other drugs at the same time, the effects of the Signoflam tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Inform your doctor about all the medicine, vitamins, and any herbal supplements you are using, so that your doctor can help you prevent or manage drug interactions. Signoflam Tablet may interact with the following medicines and products:

  • Aspirin
  • Clopidogrel
  • Alcohol
  • Dalteparin
  • Aliskiren

Substitutes for Signoflam Tablet

Below is the list of medicines, which have the same composition, action, and form as Signoflam Tablet, and hence your doctor may prescribe any of them as a substitute to Signoflam Tablet:

  • Fenobax SP Tablet – Biomax Biotechnics Pvt Ltd
  • Ibugesic Asp 100 mg/325 mg/15 mg Tablet – Cipla Ltd
  • Willgo SP Tablet – Panacea Biotec Ltd
  • Acutec SP Tablet – Glebit Laboratories
  • Voltanec SP 100 mg/325 mg/15 mg Tablet – Cipla Ltd
  • Movace SP Tablet – Alkem Laboratories Ltd
  • Vivian A Plus 100mg/325mg/15mg Tablet – Lincoln Pharmaceuticals Ltd
  • Rexonac SP 100mg/325mg/15mg Tablet – Rexion Heathcare Pvt Ltd
  • Troyace SP Tablet – Troikaa Pharmaceuticals Ltd
  • Kapnac SP Tablet – Kaps3 Life Sciences
  • Seraheal Tablet – Ipca Laboratories Ltd
  • Acevah PS 100 mg/325 mg/15 mg Tablet – Abbott
  • Acer Plus Tablet – Aerochem Neutron
  • Tremendus-SP Tablet – Grandcure Healthcare Pvt Ltd
  • Zubol SP 100mg/325mg/15mg Tablet – Diverse Health Services
  • Flozen-AA Tablet – Mankind Pharma Ltd
  • Bignac SP Tablet – Ronyd Healthcare Pvt Ltd

If for some reason an experienced doctor is not available around you, then you can contact us here.


Signoflam - Composition, Uses, Side-Effects, Substitutes, Warnings
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