PLIVA 433 – Composition, Uses, Side-Effects, Warnings

Pill with Pliva 433 printed on it is a prescription-only medication recommended to patients who are suffering from depressive disorders, mood swings, anxiety disorder etc. Get to know how PLIVA 433 works, its side effects, precautions, and contraindications where PLIVA 433 is not suggested.

What Is PLIVA 433 Pill?

PLIVA 433 Pill is an Antidepressant medication and belongs to the class of drugs called Phenylpiperazine Antidepressants. This tablet has an imprint of its name on it as PLIVA 433. PLIVA 433 Pill is categorized into Pregnancy Category C drug by FDA and it comes under the CSA (Controlled Substance Act). 

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White Pill Pliva 433 Composition

Pliva 433 ingredients are –

Pliva 433 IngredientsTrazodone 50 mg
Supplied byMajor Pharmaceuticals
Form of the MedicineTablet
Type of DrugAntidepressant medication
Parents Health Insurance Plans

PLIVA 433 White Pill Identifier

According to Pill Identifier Pliva 433 Pill is identified as Trazodone Hydrochloride 50 mg tablet with an imprint of PLIVA 433 on it. It is in a white round tablet form.

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PLIVA 433 Tablet Uses

This is a prescription drug recommended for managing or reliving below mentioned medical conditions:

  • Depression
  • Anxiety
  • Improve Mood
  • Fibromyalgia
  • Insomnia in some health condition

How Does PLIVA 433 Pill Work?

This drug works by restoring the normal levels of serotonin in the brain, which is involved in mood swings in depressive patients.

Pliva 433 Side Effects

Pliva 433 Pill may show some side effects apart from the intended benefits. It is advised to consult your doctor immediately if any side effects occur and prolong. Mentioned below are some possible side effects of Pliva 433 Pill.

  • Nausea
  • Vomiting
  • Diarrhea
  • Drowsiness
  • Dizziness
  • Tiredness
  • Blurred vision
  • Changes in your weight
  • Headache
  • Muscle pains
  • Dry mouth
  • Bad taste in the mouth
  • Stuffy nose
  • Constipation
  • Change in sexual desire or/ and ability

Some Serious side effects may be like:

  • Tremors
  • Nightmares
  • Ringing in the ears
  • Problems urinating
  • Blood in urine
  • Fever
  • Sore throat
  • Shortness of breath
  • Stomach or abdominal pain
  • Chest pain
  • Fainting
  • Irregular heartbeat
  • Seizures
  • Eye pain or swelling redness
  • Widened pupils
  • Vision changes
  • Rashes
  • Severe dizziness
  • Trouble breathing

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Precautions Before Using PLIVA 433 Pill

Pliva 433 Pill is a prescription medication. Let your doctor know about any other medication that you are using currently including any health supplements and about any other health condition you are suffering to avoid complications. Your doctor may modify the prescription based on your health conditions. Let your doctor know about health conditions such as – 

A family history of any conditions like:

  • Bipolar disorder
  • Suicide attempts
  • Heart-related health issues
  • Liver disease
  • Kidney disease
  • Blood pressure problems
  • Glaucoma

PLIVA 433 Dosage

Initial recommended dosage for an adult patient is 150mg at max in a day divided into several doses. Your doctor may prescribe an increment of 50mg per day every 3 to 4 days depending on the response level and severity of the health condition that has been tread for. And the maximum prescription dosage would be 600mg per day divided into several doses. 

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Possible Drug Interactions of Pliva 433 Pill

While some drugs are used to treat certain medical conditions, there is a possibility of drug interactions if used along with some other medication which may result in adverse side effects too. It is recommended to share the information about any medication or supplements or any health products for proper diagnosis and treatment. Don’t make any changes in dosage without consulting your doctor. Below mentioned are few examples that PLIVA 433 has the possibility of showing drug interactions.

  • Abilify (Aripiprazole)
  • Adderall (Amphetamine / Dextroamphetamine)
  • Ambien (Zolpidem)
  • Amitriptyline
  • Ativan (Lorazepam)
  • Benadryl (Diphenhydramine)
  • Celexa (Citalopram)
  • Clonazepam
  • Cymbalta (Duloxetine)
  • Fish Oil (Omega-3 Polyunsaturated fatty acids)
  • Flexeril (Cyclobenzaprine)
  • Klonopin (Clonazepam)
  • Lamictal (Lamotrigine)
  • Lexapro (Escitalopram)
  • Lyrica (Pregabalin)
  • Melatonin
  • Nexium (Esomeprazole)
  • Norco (Acetaminophen/ Hydrocodone)
  • Oxycodone
  • Prozac (Fluoxetine)
  • Seroquel (Quetiapine)
  • Suboxone (Buprenorphine / Naloxone)
  • Synthroid (Levothyroxine)
  • Topamax (Topiramate)
  • Tylenol (Acetaminophen)
  • Vitamin B12 (Cyanocobalamin)
  • Vitamin D3 (Cholecalciferol)
  • Wellbutrin (Bupropion)
  • Xanax (Blprazolam)
  • Zoloft (Sertraline)

What is Pregnancy Category-C Drug?

According to the FDA, the drugs grouped under this section are those, which have shown an adverse effect on the fetus in animal studies, but there are no adequate and well-controlled studies in humans. It is not recommended in pregnancy unless strongly needed and the benefits outweigh risks involved.


  • It is advised to keep close monitoring of your pulse and blood pressure.
  • This drug must be used in pregnancy only if the benefits overweigh the side effects.
  • Similarly in the case of breastfeeding women also this medicine is recommended if strongly needed and the benefits overweigh the side effects.
  • If you missed a dose, it is advised to take it sooner possible, and if it is nearing the next dosage schedule, skip the missed dose and continue with regular dose.
  • Regular observation by your doctor is advised while using this medicine.

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FAQs About Pliva 433 Pill

Is Pliva 433 a sleeping pill, Can I use Pliva 433 Pill for sleep, and what is Pliva 433 dosage for sleep?

No, Pliva 433 is not a sleeping pill. Pliva 433 Pill is not a first-line medication prescribed generally to address the insomnia issue. It is the medication prescribed to treat psychological disorders like depression. But your doctor may prescribe it to address the sleep disorder which may be caused due to several clinical reasons. You can use this for addressing the sleep only if your doctor decides that medication is right choice for your condition and the dosage for that also will be decided by your doctor depending on your condition. 

What If I Missed a Dose of Pliva 433?

Missing a single dose of Pliva 433 Pill may not result in adverse effects. Take your missed dose sooner you remember, and never take if it is already nearing the next dose schedule. Never take an extra dose to cover the missed one, but just continue with the regular schedule. Make it a habit of setting a reminder if you tend to forget the schedule too often. 

What if Pliva 433 Overdose Happens?

It is advised to follow the dosage as per the prescription and never overdose Pliva 433 Pill. Pliva 433 overdose can result in fatal health issues particularly if taken along with alcohol consumption or other medications like sedatives. Symptoms of Pliva 433 overdose may include excessive drowsiness, vomiting, increased heartbeats, breathing difficulty, prolonged penile erection with pain. Consult your doctor immediately if any symptoms of overdose appear to avoid further risks.

Pliva 433 vs Xanax, are both the medication same?

No, Pliva 433 Pill and Xanax are two different medications but used to treat similar health conditions. Trazodone which is a key ingredient in Pliva 433 Pill is an antidepressant medication that belongs to the class of medicine called Selective Serotonin Reuptake Inhibitors (SSRIs). Alprazolam which is a key ingredient in Xanax is a sedative medication that belongs to the class of medicine called Benzodiazepines. Xanax is considered as more prone to cause drug abuse compared to Pliva 433 Pill. 

Pliva 433 Is It A Narcotic?

No, Pliva 433 pill is not a narcotic medication and not an addictive medication. 

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PLIVA 433 - Composition, Uses, Side-Effects, Warnings
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