Levofloxacin Uses, Side Effects and Dosage


Levofloxacin is a broad-spectrum antibiotic (fluoroquinolones) drug used to treat a variety of conditions like infections of tonsils, nose, sinus, throat, urinary tract, female genital organ, skin, and soft tissues, windpipe, and lungs (pneumonia) etc. Get to know how Levofloxacin works, its side effects, precautions, and contraindications where Levofloxacin is not suggested.

About Levofloxacin

It should be contraindicated if you are known to be allergic to Levofloxacin or any other fluoroquinolones. This medicine should be used with caution in the elderly population such as 60 years of age due to increased risk of tendinitis and tendon rupture.

Levofloxacin is available in the form of tablets, oral solutions or eye drops. It can also be administered intravenously. The doctor will prescribe instructions for taking Levofloxacin according to your disease, the severity of that condition and the other medicines you are taking. It is essential to complete the course that the doctor prescribes, even if the signs and symptoms disappear, or else the infection might recur. If you forgot to take the medication do not double up the dosage, taking excess medicine can lead to overdosing.

1. How does Levofloxacin work?
2. Uses
3. Side effects
4. Contraindications
5. Doctors’ advice
6. Levofloxacin Dosage
7. Precautions while taking Levofloxacin
8. Substitutes for Levofloxacin tablet

How does Levofloxacin work?

Levofloxacin belongs to a class of medications called fluoroquinolone antibiotics. A class of drugs is a group of medications that work in a similar way. These medicines are often used to treat similar conditions.

Levofloxacin works by killing the bacteria that are causing an infection by inhibiting the DNA replication. You should only use this drug to treat bacterial infections.

Levofloxacin Uses

Levofloxacin is used to treat bacterial infections in adults and also to control, prevention, & improvement of the following diseases, conditions, and symptoms:


Levofloxacin is used in the treatment of cystitis which is a bladder infection caused by Pseudomonas aeruginosa, Enterococci E.coli, and Klebsiella pneumoniae.


Levofloxacin is used in the treatment of community-acquired pneumonia which is a most common type of lung infection caused by Haemophilus influenzae and Streptococcus pneumoniae.


Levofloxacin used in the treatment of Pyelonephritis which is a type of kidney infection caused by E.coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Enterococci.


Levofloxacin used in the treatment of Nongonococcal urethritis which is an inflammation of urethra caused by E.coli, Pseudomonas aeruginosa, and Klebsiella.


Levofloxacin used in the treatment of bronchitis which is an inflammation in lungs caused by Haemophilus influenzae, Streptococcus pneumoniae, and some Mycoplasma pneumoniae.

Skin and Structure Infection

Levofloxacin is used in the treatment of Skin and Structure infection like cellulitis, wound infection and cutaneous abscess caused by Staphylococcus aureus and Streptococcus pyogenes.

  • Pneumonia
  • chronic bronchitis
  • Sinus infection
  • Skin infections
  • Gastroenteritis
  • Urinary tract infections
  • Pyelonephritis (kidney infection)
  • Chronic prostate infection
  • Plague
  • Inhalational anthrax
  • Anthrax
  • Plague
  • Cystitis
  • Pyelonephritis

Levofloxacin may also use as a part of a combination therapy. This means you may need to take it with other drugs.

Levofloxacin side effects

In addition to its intended results, Levofloxacin drug may cause some unwanted effects too. In such cases, you must seek medical attention right away. This is not an exhaustive list of side effects. Please call your doctor if you find any adverse reaction to the medication.

Some common side effects may include:

  • Nausea
  • Headache
  • Rashes
  • Diarrhea
  • Vomiting
  • Drowsiness and trouble sleeping

A few people experience severe side effects such as tremors, insomnia, seizures, anxiety, depression, suicidal thoughts, severe headaches tendonitis, peripheral neuropathy, anaphylaxis, liver damage, gastrointestinal disorders and heart problems. If you detect any of the side effects mentioned above. You should seek emergency medical expertise as soon as possible.

Contraindications for Levofloxacin


This drug is not recommended for use if you have a known allergy to Levofloxacin or any other fluoroquinolones.

Tendon rupture or Tendinitis

This drug is not recommended for use if you have a past history of tendinitis or tendon rupture after using Levofloxacin or any other fluoroquinolones.

Myasthenia gravis

Levofloxacin is not recommended for use if you have a past history of myasthenia gravis or family history of myasthenia gravis (weakness and rapid tiring of muscles which are under voluntary control).

Doctors’ advice for levofloxacin

  • Never take antibiotic medicines for a viral infection like a cold or the flu.
  • Always take the complete course of treatment, as advised by your doctor even if you feel better.
  • If you notice any side effects; stop taking Levofloxacin immediately and consult your doctor.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Inform your doctor if you have ever been diagnosed with kidney, epilepsy or heart diseases.

Levofloxacin Dosage

The dose of Levofloxacin will be differing from patient to patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells for oral dosage forms (oral solution or tablets):

For treatment of an infection:

  • Adults—250 to 750 mg (milligrams) once a day.
  • Children—Use and dose must be determined by your doctor.

For preventing anthrax infection:

  • Adults—500 mg (milligrams) once a day.
  • Children 6 months of age and older and weighing more than 50 kg (kilograms)—500 mg once a day.

For treatment and prevention of plague:

  • Adults—500 mg (milligrams) once a day.
  • Children 6 months of age and older, weighing more than 50 kg (kilograms)—500 mg once a day.
  • Take with a full glass of water
  • This medicine can be administered without regard to the timing of meals
  • If you miss the dosage take as soon as possible, and if it is near to next dose, skip the missing dosage continue the regular dosage. Do not take extra doses.

Precautions while taking Levofloxacin

Before taking Levofloxacin, tell your pharmacist or doctor if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your doctor for more information.

Before using this Levofloxacin, tell your doctor or pharmacist your medical history, especially of: severe kidney problems, have a history of tendon problems (eg, rheumatoid arthritis), or have received an organ (example; heart, kidney, or lung) transplant.

Before having this medicine, tell your doctor about all the products you use (including herbal products, prescription drugs, and non-prescription drugs).

During pregnancy, Levofloxacin should be used only when clearly needed. Discuss the benefits and risks with your doctor.

It is unknown if Levofloxacin passes into breast milk. Discuss the risks and benefits with your doctor before breastfeeding.

Substitutes for Levofloxacin tablet

Below is the list of medicines, which have the same composition, strength, and form as Levofloxacin and hence can be used as its substitute:

  • Alevo 500 MG Tablet–Alkem Laboratories Ltd
  • Levovista 500 MG Tablet–Cadila Pharmaceuticals Ltd
  • Lufi 500 MG Tablet–Ipca Laboratories Pvt Ltd
  • Levloc 500 MG Tablet–Cadila Pharmaceuticals Ltd
  • Zentor 500 MG Tablet–Zuventus Healthcare Ltd

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