Jardiance

Jardiance

Table of Contents

  1. What is Jardiance?
  2. Constituents
  3. Indications
  4. How does Jardiance work?
  5. How to Take Jardiance?
  6. Common Dosage for Jardiance?
  7. When to Avoid Jardiance?
  8. Side-effects of Jardiance?
  9. Effects on organs?
  10. Reported Allergic Reactions?
  11. Effect on menstrual cycle?
  12. Drug Interactions To Be Careful About
  13. Food interactions (if any)
  14. Interactions with laboratory procedures
  15. Shows Effects / Results In and how long does the effect stay:
  16. Is Jardiance Addictive?
  17. Can I have Jardiance with alcohol?
  18. Can I have Jardiance When Pregnant?
  19. Can I have Jardiance when feeding a baby?
  20. Can I drive after taking Jardiance?
  21. Effect of overdose of Jardiance?
  22. Effect of using expired Jardiance?
  23. Effect of missing a dose of Jardiance?
  24. Storage requirements
  25. Substitutes for Jardiance
  26. Expert comments

What is Jardiance?

Jardiance is a prescription medicine recommended to be used in the treatment of type 2 diabetes mellitus in adult patients. This medicine is generally prescribed as a combination therapy along with other medicine or alone as an individual medication depending on the patient’s health condition. For best results, it is advised to use this medicine along with a proper guided diet plan and exercise regime.

Type of drug

The key ingredient Empagliflozin belongs to the class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors.

Use in brief

Jardiance) is prescribed to be used as an anti-diabetic medication in case of Type 2 diabetes mellitus. It should not be used in type 1 diabetes.

Constituents

Jardiance tablets contain Empagliflozin as an active ingredient.

Jardiance tablets are also available in different variations and in combination with other molecules as active ingredients. Below are some examples of different compositions.

Jardiance Tablets with Empagliflozin as an active ingredient

  • Jardiance 25 mg Tablet – (Empagliflozin 25mg)
  • Jardiance 10 mg Tablet – (Empagliflozin 10mg)

Jardiance Tablets with Empagliflozin and Metformin as active ingredients

  • Jardiance Met 5mg/500mg Tablet – (Empagliflozin 5mg + Metformin 500mg)
  • Jardiance Met 12.5mg/500mg Tablet – (Empagliflozin 12.5mg + Metformin 500mg)
  • Jardiance Met 12.5mg/1000mg Tablet – (Empagliflozin 12.5mg + Metformin 1000mg)

About Metformin

Metformin is a prescription medicine widely used to treat type 2 diabetes particularly for patients who are overweight. Other than type 2 diabetes Metformin is also prescribed to treat polycystic ovary syndrome

Manufactured by – Jardiance is manufactured by Boehringer Ingelheim Pharmaceutical Company.

Indications

Jardiance tablets are prescribed to treat type 2 diabetes mellitus.

How does Jardiance work?

This medicine basically belongs to anti-diabetic drugs and works by removing the excess amount of sugar present in the body through urine.

How to Take Jardiance?

Form of medicine – Jardiance medicine is available in the form of tablets

When and How to use

Follow the instructions as mentioned in the prescription. Follow regular schedule to take the medication. Never skip a dose.

Never crush or chew the tablet but swallow the whole medicine along with some water or liquids. This medicine can be used with or without food based on the prescription.

Common Dosage for Jardiance

The dosage depends on the diabetic levels of the patient and is decided by the doctor. Follow the dosage instruction by your doctor. Never miss a dose or take an excess dose. Consult your doctor immediately if any excess dosage happens by mistake.

When to Avoid Jardiance?

Jardiance is not advised to use in some health conditions such as:

  • Type 1 diabetes
  • Diabetic ketoacidosis
  • Allergic symptoms towards the active ingredients of the medication.
  • In case of severe renal impairment

Side-effects of Jardiance

Jardiance may possibly show some side effects in some patients. It is advised to consult your doctor if any of such side effects are noticed and if they are prolonged. Below mentioned are some possible side effects by Jardiance.

  • Nausea
  • Frequent urge to urinate
  • Increased thirst
  • Dizziness
  • Weakness
  • Urinary tract infection
  • Genital fungal infection
  • Low blood sugar levels (Hypoglycaemia) may occur if used in combination with insulin or Sulphonylurea

Side-effects of Jardiance in case of the combination of Empagliflozin and Metformin as an active ingredients

  • Nausea
  • Vomiting
  • Taste change
  • Diarrhea
  • Yeast infections
  • Urinary tract infection

Effects on organs

This medicine may possibly show adverse effects on organs like kidney and liver if overdosed. It is advised to use with extreme precautions and medical supervision in case of severe health disorders or impairment related to kidneys or liver. It is advised to consult the doctor and share detailed information about your current health condition so that the doctor can alter the dosage depending on your health condition.

Reported Allergic Reactions?

No major allergic reactions are noticed in case of Jardiance.

Effect on menstrual cycle

Generally, no effect noted on the menstrual cycle. You may consult your gynaecologist.

Drug Interactions to Be Careful About

Jardiance may possibly show drug interaction with other medication if they are used together. It is advised to share the medication details that you might be using any with your doctor before he prescribes this medicine to you.

Some of the drugs with which Jardiance shows interaction include:

  • Paroxetine
  • Collagen Peptide
  • Propranolol
  • Methylprednisolone
  • Pancreatin
  • Diacerein
  • Betamethasone
  • Deflazacort
  • Escitalopram Oxalate
  • Dexamethasone

Food interactions

No major food interactions observed.

Interactions with laboratory procedures

There is no interaction noticed with any diagnostic test while under the medication but it is always good to share details about your current medication before attending any lab tests so that your doctor and lab technician is aware of.

Shows Effects / Results in and how long does the effect stay

The onset of action for this medicine is 1.5 hours. It can show the results in 1.5 hours after taking the medication. The duration of the effect is not clinically established.

Is Jardiance Addictive?

No drug addiction is noticed in case of Jardiance.

Can I have Jardiance with alcohol?

It is not advised to use Jardiance tablets along with alcohol as it might alter the blood glucose levels.

Can I have Jardiance When Pregnant?

Not advised to use in general in pregnant women and it may show adverse effects on the fetus. But with consultation and supervision in case if unavoidable and the intended benefits are more compared to possible side effects.

Can I have Jardiance when feeding a baby?

Not advised to use in general in breastfeeding women. But with consultation and supervision in case if unavoidable and the intended benefits are more compared to possible side effects.

Can I drive after taking Jardiance?

If the blood glucose levels are low or high, the mental and physical alertness may be affected. In such conditions, it is not advised to do activities such as driving which require alertness.

Effect of overdose Jardiance

Serious adverse effects such as hypoglycemia may be possible if overdosage happens in large quantities. Consult your doctor immediately in such situations.

Effect of using expired Jardiance?

It is advised not to use any medicine that is expired to avoid any adverse effects. Consult your doctor immediately if any adverse effects are noticed by taking any expired medicine. It is advised to check the label while purchasing the medicine to verify the expiry date to be safe.

Effect of missing a dose of Jardiance

No major adverse effects are noticed if only one dosage is missed. But if you are missing the dosages regularly, it is advised to keep a reminder so that you don’t miss the regular dosage.

Storage requirements

It is advised to store the medication away from direct sunlight and to keep at room temperature. Keep away from the reach of the children and pets.

Substitutes for Jardiance

Below mentioned brands of medicine is with similar composition and strength, hence your doctor may prescribe this as an alternate option to treat your condition.

  • Gibtulio Tablet – Manufactured by Lupin Ltd

Expert comments

  • Jardiance should always be initiated with a low dose and the dose can be increased later if needed. Jardiance does not cure diabetes but it just controls it so do not stop taking Jardiance without consulting your doctor.

If for some reason an experienced doctor is not available around you, then you can contact us here.

Dr. Srishti Tayal is Chief Radiologist at Radiodent – Dental and Maxillofacial Imaging. She has completed BDS and MDS with Gold Medal from JSS Medical College, Mysore. She is a passionate medical researcher and has published five research papers in various medical journals and received an award for the best scientific paper.

In addition to following her pursuits in dentistry, she is also an avid medical writer who believes in bridging the information gap among the common population with regards to modern medicine.

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