Table of Contents
- What are Green Xanax Bars?
- How does Xanax work?
- Common Dosage for Xanax
- Contraindications of Xanax
- Side-effects of Xanax
- Effects on organs
- Reported Allergic Reactions
- Effect on the menstrual cycle
- Drug Interactions To Be Careful About
- Food interactions
- Interactions with laboratory procedures
- Shows Effects / Results In and how long does the effect stay:
- Is Xanax Addictive?
- Can I have Xanax with alcohol?
- Can I have Xanax when Pregnant?
- Can I have Xanax when feeding a baby?
- Can I drive after taking Xanax?
- Effect of an overdose of Xanax
- Effect of using expired Xanax
- Effect of missing a dose of Xanax
- Storage requirements
- Substitutes for Xanax
- Expert comments
What is Xanax?
Green Xanax Bars are rectangular pills imprinted as ‘S 90 3’. Alprazolam 2mg is the drug in the pills. It is manufactured by Dava pharmaceuticals. Green Xanax is mainly used for treating anxiousness, panic attacks, and depression. It belongs to the drug class Benzodiazepines.
Green Xanax bars contain alprazolam as a main ingredient and cellulose, corn starch, lactose, silicon dioxide and sodium benzoate as inactive ingredients. It is available as tablet form with dosages 0.25mg, 0.5mg, 1mg, 2mg.
How does the medicine look like:
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US FDA approved Indications:
- Green Xanax bars are prescribed to treat anxiety
- Anxiety with depression can also be treated with Green Xanax.
- Panic disorder is another indication of Xanax.
NON-FDA approved Indications:
- Premenstrual syndrome
How does Xanax work?
Alprazolam belongs to a class of psychoactive medications called Benzodiazepines. The therapeutic effects of Alprazolam are produced by binding GABA- Benzodiazepine receptors in the brain. The neurotransmitter GABA, when bound to the GABA receptor, results in the inhibitory or calming effects.
Common Dosage for XANAX
- For anxiety: Usual initial dose for treatment of anxiety is 0.25 to 0.5 mg given three times daily. To achieve a maximum therapeutic effect, the dose can be increased to 4mg per day in divided doses.
- For panic disorders: For panic disorders, the dose required is greater than 4mg per day.
- In patients with liver disorders and other debilitating diseases, the dose suggested is 0.25mg thrice daily.
How to take Xanax
- Xanax is available as a regular release and orally disintegrating tablets in strengths of 0.25 mg, 0.5 mg, 1 mg, and 2 mg tablets,
- Extended-release tablets are available in strengths of 0.5 mg, 1mg, 2mg, and 3 mg.
- Xanax is also available as an oral solution in strengths of 0.5 mg/5 mL and as 1 mg/10mL.
- It can be taken at any time of the day before or after food. In order to avoid stomach upset, it is better to take it with food.
- Do not chew the extended-release tablets. They should be swallowed as a whole.
- Other Benzodiazepines include- Clonafit, alprazolam (Xanax, Xanax XR), clobazam (Onfi), clonazepam (Klonopin), clorazepate (Tranxene), chlordiazepoxide (Librium), diazepam (Valium)
Contraindications of Xanax
- XANAX Tablets are contraindicated in patients allergic to alprazolam or other benzodiazepines.
- Xanax may cause an increase in intra-ocular pressure. Hence it is contraindicated in acute closure angle or untreated open-angle glaucoma.
- Xanax is contraindicated along with cytochromeP4503A4 inhibitors like Ketaconazole, Itriconazole.
Cyp3A4 mediates the metabolism of many drugs like Xanax. Using Xanax along with cyp3A4 inhibitors will interfere with the metabolism and clearance of the drug.
Side-effects of Xanax
- The risk of dependence is higher in patients undergoing treatment for panic disorders because the treatment requires doses higher than 4mg per day. Withdrawal of the drug can lead to a relapse of the symptoms similar to panic attacks before the treatment has started.
- Anxiety and symptoms of anxiety between the doses of XANAX have been reported in patients with panic attacks. Though it is taken in prescribed doses.
- CNS Depression: Because of its CNS depressant effects, patients receiving XANAX should be careful while operating machinery or driving a motor vehicle. For the same reason, Xanax along with alcohol and other CNS depressants is not recommended.
Reported Allergic Reactions
- Trouble breathing
- Swelling of your face, lips, tongue, or throat is the allergic reaction observed in some cases. Please contact your doctor if any of these signs are observed.
Effect on the menstrual cycle
No sufficient data is available to determine any effects on the menstrual cycle.
Drug Interactions to Be Careful About
- CYP3A inhibitors-Azole antifungal agents like Ketoconazole and itraconazole are potent CYP3A inhibitors.
- Fluvoxamine-Coadministration of fluvoxamine approximately doubles the maximum plasma concentration of alprazolam
- Cimetidine-Coadministration of cimetidine increases the maximum plasma concentration of alprazolam
- Other drugs which
interfere with the metabolism and clearance of Xanax are:
- Imipramine and Desipramine
- Oral Contraceptives.
- Macrolide antibiotics,
- Rifamycins, St. John’s wort.
- Seizure medications (carbamazepine, phenytoin)
- Antihistamines and muscle relaxants.
Tell your doctor the list of medications and treatments you are undergoing.
Talk to your doctor about drinking grapefruit juice or eating grapefruit while taking this medication, because grapefruit may reduce the metabolism of Xanax (grapefruit is an inhibitor of cyp3A4 which helps in the metabolism of Xanax).
Interactions with laboratory procedures
No consistent interactions with any specific laboratory procedures.
How long does it stay in your body?
One tablet of Xanax can stay in your body for up to 3 days.
Is Xanax addictive?
Tolerance to this drug is very quick and the patient might need to take a number of pills to achieve the efficacy needed within very few days after the treatment has started. This will eventually lead to addiction to this medicine. If the patient stops taking Xanax, they may experience withdrawal symptoms such as anxiety, restlessness, insomnia, and tremors. The onset of withdrawal symptoms is a sign that physical dependence has started.
Can I have Xanax with alcohol?
The use of alcohol and/or illegal drugs with Xanax increases the chances of life-threatening side effects. Hence use of Xanax along with alcohol is contraindicated.
Can I have Xanax when Pregnant?
Benzodiazepines can potentially cause fetal harm when taken by pregnant women.
Can I have Xanax when feeding a baby?
Prolonged administration of Xanax in nursing mothers may cause their infants to lose weight and be lethargic. Hence Xanax is not recommended while Breast feeding.
Can I drive after taking Xanax?
As this drug may cause drowsiness and sedation, depending on the dosage your doctor may caution you to either avoid driving or be careful while driving or working with heavy machinery.
Effect of an overdose of Xanax
Some of the Manifestations of overdosage include somnolence, confusion, impaired coordination, diminished reflexes and coma.
Effect of using expired Xanax
If you take an expired Xanax, please contact your doctor. Expired Xanax may not show the intended efficacy.
Effect of missing a dose of Xanax
If you remember the missed dose close to the next regular dose, then skip the dose and take the regular dose.
Store at room temperature 20 to 25deg C(68 F to 75 F). Keep it away from children.
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Dr. Divya has been pursuing Dentistry for about 5 years now. Endodontics and Orthodontics are her areas of interest and she holds a BDS degree from Govt. Dental College, Vijayawada, AP. Besides pursuing her career as a Dentist, she is passionate about Technical writing and is spending her free time in writing medical articles to bring awareness and share medical knowledge to the public.