Duopep – Composition, Uses, Side-Effects, Substitutes, Warnings

Table of content

  1. What is Duopep?
  2. How Does Duopep Work?
  3. Duopep Composition and Active Ingredients
  4. Duopep Uses 
  5. Side Effects of Duopep Tablet
  6. Duopep Contraindications
  7. Duopep Dosage
  8. Duopep Precautions
  9. General warnings about Duopep Tablet
  10. Drug interactions of Duopep tablet
  11. Substitutes for Duopep Tablets

What is Duopep?

Duopep Tablet is a proton-pump inhibitor drug. It is used for acidity, heartburn, gastric ulcer, Gastroesophageal reflux disease, intestinal ulcer, esophageal mucosal injury, benign gastric ulcer, benign duodenal ulcer, Oesophagus inflammation, stomach ulcers, and other conditions. Get to know how Duopep works, its side effects, precautions, and contraindications where Duopep is not suggested.

How Duopep tablet Works?

The mechanism of action is by inhibiting the acid production in the stomach, thereby helps in relief of acid-related indigestion and heartburn.

Duopep tablet Composition and Active Ingredients

Composition – Pantoprazole 40mg is an active ingredient in Duopep Tablet.
Manufactured By – Duopep tablet is manufactured by marketed by Apex Laboratories Pvt Ltd.
Prescription – Prescription is required, this is a prescription medicine and should be taken on the prescription of Registered Medical Practitioner.
Available in the Forms – This medicine is available in the form of tablets.
Drug Type – Pantoprazole which is a key ingredient in this medicine belongs to the class of medicine called Proton Pump Inhibitor (PPI)
Duopep Tablets are available in below-mentioned variations

  • Duopep 40 mg Tablet – (Composition – Pantoprazole (40mg)) and available as 10 tablets per strip.

Duopep Tablet Uses and Benefits

This medicine is beneficial to treat a variety of acid issues as discussed below:

Gastric Ulcer

Effective in treating gastric ulcers that are characterized by sores in the stomach lining or duodenum.

Peptic Ulcer

Duopep tablet is effective in peptic ulcers treatment, which develops on the lining of the stomach, Oesophagus and small intestine.

Esophageal Mucosal Injury

Esophageal Mucosal Injury is an injury caused by GERD (Gastro-esophageal Reflux Disease), which leads to increase in gastric juice to the esophagus (food pipe or gullet). However, it can be treated with Duopep.

Gastrinoma/ Gastrin- Secreting Tumor

Prescribed to treat early stages of Gastrinoma cancer.

Duopep Tablet During Pregnancy

Pregnancy induces a surge of various hormones, which may lead to various imbalances in body including frequent acid refluxes and gastric issues. Normally, Duopep tablet is safe for pregnant women to cure acid reflux.

Helicobacter Pylori Infection

Duopep is very useful in treating Helicobacter pylori infection. Helicobacter pylori are bacteria spiral in shape, which grows in the digestive tract and infects stomach linings.

Zollinger-Ellison Syndrome

Duopep Tablet is used to treat Zollinger-Ellison Syndrome which is a condition where an excessive amount of acid is produced in the stomach due to tumors in the small intestines.

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Duopep Tablet Side effects

Although Duopep tablet is one of the most effective medicine to treat gastrointestinal disorders and acid reflux, it has certain limitations. Consult your physician in case you experience any of the below symptoms:

Running nose and sore throat Cough – Duopep tablet can cause irritation in the throat and nasal tract.
Headache And Nausea, Vomiting – In the case of children, Duopep tablet can cause these problems.
Loss of appetite – Duopep tablet may lead to food averseness and make you undernourished. It can also create metallic taste with dry mouth.
Diarrhea – Sometimes, you may experience loose stools with other stomach discomforts such as pain and flatulence.
Skin Infection – This tablet sometimes can lead to skin rash and swelling.

Contraindications for Duopep Tablet

Do not this medicine if you are suffering from the following condition:

  • Allergy to Duopep tablet and its ingredients
  • Atrophic gastritis
  • Interstitial nephritis
  • Low amount of magnesium in the blood
  • Broken bone
  • Clostridium difficile bacteria related colitis
  • Inadequate vitamin B12

Duopep Tablet Dosage

It is not an OTC (over-the-counter) medicine and does require a prescription from a qualified doctor. Duopep should be swallowed as a whole with water and usually at a fixed time of the day.

Precautions Before Taking Duopep Tablet

  • Use this tablet only if prescribed by the physician
  • Do not consume alcohol while using Duopep tablet which can increase the risk of stomach damage.
  • Take the full course of treatment
  • Tell your doctor if you are taking any medication or are suffering from any disease
  • Do not take Duopep tablet if you are allergic to any of the ingredients of this medicine or any of their excipients
  • Do not take this Duopep tablet after the expiry date stated on the carton package
  • Keep this medicine out of the reach of children.

General Warnings


Taking more than prescribed Duopep tablet may cause harmful side effects. Consult your physician or pharmacist if you find any side effects.

What if You Missed a Dose?

If a regular dose is missed out by mistake, try to take it as soon as you remember. If it is nearing the next scheduled time, then just skip the missed one and continue with the next scheduled one. Do not take extra doses.


Duopep tablet is not recommended for use in pregnant women unless necessary and the potential benefits outweigh the risks involved. Duopep tablet is not known to cause any harm to the fetus, but should only be used after consultation with your physician.


Duopep tablet is safe to use during breastfeeding. Before taking Duopep tablet, consult your physician.

Duopep Tablet Drug Interactions

If you use other over the counter products or other drugs at the same time, the effects of the Duopep Tablet may change. Moreover, this might lead to a higher risk of getting side effects, and this medicine might be less effective. Tell your physician about all the drugs, vitamins, and herbal supplements you are using, so that your physician can help you prevent or manage drug interactions. Duopep Tablet may interact with the following medicines and products:

  • Lorazepam
  • Diazepam
  • Alprazolam
  • Nitrazepam
  • Clobazam
  • Clonazepam
  • Roxithromycin
  • Clopidogrel
  • Phenytoin
  • Methotrexate

Substitutes for Duopep Tablet

Here is the List of substitute’s medicines which have the same composition, strength, and form as Duopep tablet:

  • Pantakind 40mg Tablet – Mankind Pharma Ltd
  • Panplus 40mg Tablet – Alembic Pharmaceuticals Ltd
  • Aciban 40mg Tablet – Cadila Pharmaceuticals Ltd
  • Pantin 40mg Tablet – Hetero Drugs Ltd
  • Panto 40mg Tablet – Micro Labs Ltd
  • Pantocid 40mg Tablet – Sun Pharmaceutical Industries Ltd

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Duopep - Composition, Uses, Side-Effects, Substitutes, Warnings
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