Dapagliflozin

Dapagliflozin

Table of Contents

  1. What is Dapagliflozin?
  2. Constituents
  3. Indications
  4. How does Dapagliflozin work?
  5. How to Take Dapagliflozin?
  6. Common Dosage for Dapagliflozin?
  7. When to Avoid Dapagliflozin?
  8. Side-effects of Dapagliflozin?
  9. Effects on organs?
  10. Reported Allergic Reactions?
  11. Effect on menstrual cycle?
  12. Drug Interactions To Be Careful About
  13. Food interactions (if any)
  14. Interactions with laboratory procedures
  15. Shows Effects / Results In and how long does the effect stay:
  16. Is Dapagliflozin Addictive?
  17. Can I have Dapagliflozin with alcohol?
  18. Can I have Dapagliflozin When Pregnant?
  19. Can I have Dapagliflozin when feeding a baby?
  20. Can I drive after taking Dapagliflozin?
  21. Effect of overdose of Dapagliflozin?
  22. Effect of using expired Dapagliflozin?
  23. Effect of missing a dose of Dapagliflozin?
  24. Storage requirements
  25. Available brands of Dapagliflozin
  26. Expert comments

What is Dapagliflozin?

Dapagliflozin is a prescription medicine used to treat type 2 diabetes mellitus. Generally, it is prescribed along with other medication or alone depending on the patient’s health condition. For best results, it is always advised to use Dapagliflozin along with lifestyle change (controlled diet, quitting smoking and exercise plan).

Dapagliflozin should not be used in the treatment of type 1 diabetes and diabetic keto-acidosis.

Type of drug

Dapagliflozin belongs to Sodium-Glucose Co-Transporter 2 (SGLT2) inhibitors group of medication.

Use in brief

Dapagliflozin is prescribed to use as an anti-diabetic medication in type 2 diabetes patients.

Constituents

Dapagliflozin itself is an active ingredient in different brands used to treat type 2 diabetes mellitus.

Indications

Dapagliflozin is prescribed to treat Type 2 Diabetes mellitus

How does Dapagliflozin work?

Dapagliflozin lowers blood sugar by removing the excess amount of sugar in the body through urine.

How to Take Dapagliflozin?

Form of medicine – Dapagliflozin medicine is available in the form of tablets.

When and How to use

Follow the instructions as mentioned in the prescription. It can be administered with or without food usually once a day in the morning.

Never crush or chew the tablet but swallow the whole medicine along with some water or liquids. Dapagliflozin is advised to use strictly as per the prescription and it should not be stopped suddenly without consulting the doctor.

Common Dosage for Dapagliflozin

The dosage depends on the severity of the condition and is decided by the doctor. Follow the instruction by your doctor. Never miss a dose or take an excess dose. Consult your doctor immediately if any excess dosage happens by mistake.

When to Avoid Dapagliflozin?

Dapagliflozin is not advised to use in patients suffering from some health conditions such as:

  • In case of type 1 diabetes mellitus and diabetic keto-acidosis
  • Dapagliflozin is not advised to use along with alcohol consumption
  • In case of severe hepatic impairment (liver failure)
  • In case of severe renal impairment (kidneys failure)
  • In patients suffering from bladder cancer
  • In case of severe urinary tract infection (UTI)

Side-effects of Dapagliflozin

Dapagliflozin may possibly show some side effects in some patients. It is advised to consult your doctor immediately if any of such side effects are noticed:

  • Nausea
  • Frequent urge to urinate
  • Increased thirst
  • Dizziness
  • Light headedness
  • Urinary tract infection
  • Hypoglycemia (low blood sugar level) in combination with insulin or Sulphonylurea
  • Genital fungal infection
  • Weight loss in some patients

Effects on organs

This medicine may possibly show adverse effects on organs like kidney and liver if overdosed. It is advised to use with extreme precautions and medical supervision in case of severe health disorders or impairment related to kidneys or liver conditions.

It is advised to consult the doctor and share detailed information about your current health condition so that the doctor can alter the dosage depending on your health condition.

Reported Allergic Reactions?

No major allergic reactions are noticed in case of Dapagliflozin.

Effect on menstrual cycle

Generally, no effect noted on the menstrual cycle. You may consult your gynaecologist.

Drug Interactions to Be Careful About

Dapagliflozin may possibly show drug interaction with some other medication if they are used together. It is advised to share the list of medication with your doctor that you are administering before starting Dapagliflozin.

Some of the drugs with which Dapagliflozin shows interaction include:

  • Paroxetine
  • Collagen Peptide
  • Pancreatin
  • Escitalopram Oxalate
  • Diacerein
  • Propranolol
  • Betamethasone
  • Deflazacort
  • Methylprednisolone

Food interactions (if any)

No major food interactions observed.

Interactions with laboratory procedures

There is no interaction noticed with any diagnostic test while under the medication but it is always good to share details about your current medication before attending any lab tests so that your doctor and lab technician is aware of.

Shows Effects / Results in and how long does the effect stay

The onset of action of this medicine is generally 2 hours after administration. Consult your doctor if you are concerned about the onset of action and duration of effect.

Is Dapagliflozin Addictive?

No drug addiction is noticed in the case of Dapagliflozin.

Can I have Dapagliflozin with alcohol?

It is not advised to consume alcohol while under the medication of Dapagliflozin. Consult with your doctor if you have a habit of regular intake of alcohol.

Can I have Dapagliflozin When Pregnant?

Not advised to use in general in pregnant women. But with consultation and supervision in case if unavoidable and the intended benefits are more compared to possible side effects.

Can I have Dapagliflozin when feeding a baby?

Not advised to use in general in breastfeeding women. But with consultation and supervision in case if unavoidable and the intended benefits are more compared to possible side effects.

Can I drive after taking Dapagliflozin?

In general, it may not cause dizziness but in very rare cases some patients may notice drowsiness or dizziness because of low or high blood glucose levels. In such conditions, it is not advised to do activities such as driving which require alertness.

Effect of overdose Dapagliflozin

Serious adverse effects may be possible if overdosage happens in large quantities. Consult your doctor immediately if any overdosage happens.

Effect of using expired Dapagliflozin?

It is advised not to use any medicine that is expired to avoid any adverse effects. Consult your doctor immediately if any adverse effects are noticed by taking any expired medicine. It is advised to check the label while purchasing the medicine to verify the expiry date to be safe.

Effect of missing a dose of Dapagliflozin

No major adverse effects are noticed if only one dosage is missed. But if you are missing the dosages regularly, it is advised to keep a reminder so that you don’t miss the regular dosage.

Storage requirements for Dapagliflozin

It is advised to store the medication away from direct sunlight and to keep at room temperature. Keep away from the reach of the children and pets.

Available brands of Dapagliflozin

Below mentioned brands of medicine contain Dapagliflozin as an active ingredient with similar composition and strength hence your doctor may prescribe these as alternate options to treat your condition.

  • Oxra- Manufactured by Sun Pharmaceutical Industries Ltd
  • Gledepa – Manufactured by Abbott Healthcare Pvt Ltd
  • Forxiga – Manufactured by AstraZeneca Pharma India Limited

Expert comments

  • Dapagliflozin should always be initiated with a low dose and the dose can be increased later if needed. Dapagliflozin does not cure diabetes but it just controls it so do not stop taking Dapagliflozin without consulting your doctor.

If for some reason an experienced doctor is not available around you, then you can contact us here.

Dr. Srishti Tayal is Chief Radiologist at Radiodent – Dental and Maxillofacial Imaging. She has completed BDS and MDS with Gold Medal from JSS Medical College, Mysore. She is a passionate medical researcher and has published five research papers in various medical journals and received an award for the best scientific paper.

In addition to following her pursuits in dentistry, she is also an avid medical writer who believes in bridging the information gap among the common population with regards to modern medicine.

Leave a Review

How did you find the information presented in this article? Would you like us to add any other information? Help us improve by providing your rating and review comments. Thank you in advance!

Name
Email (Will be kept private)
Rating
Comments
Dapagliflozin Overall rating: ☆☆☆☆☆ 0 based on 0 reviews
5 1

Leave a Reply

Your email address will not be published. Required fields are marked *