CLARITIN D

Claritin D

Table of Contents

  1. What is CLARITIN D?
  2. Constituents
  3. Indications
  4. How does CLARITIN D work?
  5. How to Take CLARITIN D?
  6. Common Dosage for CLARITIN D
  7. When to Avoid CLARITIN D?
  8. Side-effects of CLARITIN D
  9. Effects on organs
  10. Warnings and Precautions if any
  11. Reported Allergic Reactions
  12. Effect of CLARITIN D on the menstrual cycle
  13. Drug Interactions To Be Careful About
  14. Food interactions
  15. Interactions with laboratory procedures
  16. Shows Effects / Results in (How Long Does the Effect Stay?)
  17. Is CLARITIN D Addictive?
  18. Can I have CLARITIN D with alcohol?
  19. Can I have CLARITIN D When Pregnant?
  20. Can I have CLARITIN D when feeding a baby?
  21. Can I drive after taking CLARITIN D?
  22. Effect of an overdose of CLARITIN D
  23. Effect of using expired CLARITIN D
  24. Effect of missing a dose of CLARITIN D
  25. Storage requirements
  26. Substitutes for CLARITIN D

What is CLARITIN D?

Claritin D is a combination medicine of Loratadine and pseudoephedrine which comes as extended-release tablets. Loratadine is an antihistamine and Pseudoephedrine is a decongestant. It is both prescription-based and over the counter medicine. It is used for allergies, symptoms of a common cold like sneezing or running nose, itchy or watery eyes or nose and sinus pain, etc.

It is US FDA approved drug which comes as extended-release tablets in two strengths

  • 5mg Loratadine and 120mg Pseudoephedrine sulfate
  • 10mg Loratadine and 240mg Pseudoephedrine sulfate

Similar drugs available in the USA with the same composition:

  • Alavert Allergy and Sinus
  • Allergy relief

Constituents

  • Claritin-D: Loratadine 5 mg and pseudoephedrine sulfate 120 mg is the composition of the Claritin D used as an extended release tablet once in 12 hours for allergy and congestion.
  • Claritin-D: Loratadine 10 mg and pseudoephedrine sulfate 240 mg is the composition of the Claritin D used as an extended release tablet once in 24 hours for allergy and congestion.
Claritin D

These are the main ingredients. The inactive ingredients include calcium carbonate, carnauba wax, ethylcellulose, magnesium stearate, etc.

Indications

Claritin D is indicated in allergic rhinitis

  • To relieve congestion due to cold
  • In relieving symptoms of sinusitis

How does CLARITIN D work?

Loratadine is a long-acting antihistamine that works on a certain type of  H1 receptors and blocks the histamine release which causes allergy.  Loratadine doesn’t cross the blood-brain barrier. Therefore, it will not cause drowsiness.

Pseudoephedrine is a sympathomimetic amine that acts on alpha-adrenergic receptors and causes shrinking of swollen mucous membranes. It can be used as CNS stimulant, nasal decongestant and in promoting wakefulness.

How to Take CLARITIN D?

12-hour tablets should be taken orally after food twice daily. Take it as a whole. Do not crush or chew the tablet.

The 24-hour tablet should be taken orally once daily after food. Take it as a whole. Do not crush or chew the tablet.

Common Dosage for CLARITIN D

The usual dosage for adults and children above 12 years age is 12-hour tablet i.e. of 5mg/120mg composition twice daily and 24-hour tablet i.e. of 10mg/240mg composition once daily.

Patients with kidney problems should not take it over the counter. Your doctor may suggest different dosages for your condition. Please consult your doctor before taking this medicine if you have any history of liver and kidney problems as most of the drugs metabolize in the liver and the clearance of the drugs depend on the functioning of the kidneys.

When to Avoid CLARITIN D?

  • It is contraindicated in patients hypersensitive to the components of the tablet.
  • It should be avoided in patients with severe kidney impairment and liver failure.
  • Pseudoephedrine in this drug is contraindicated in diabetes mellitus, cardiovascular disease, uncontrolled hypertension, narrow-angle glaucoma, prostate hypertrophy, and hyperthyroidism.

Side-effects of CLARITIN D

Claritin D may cause the following side effects. Adverse effects may not occur to all the patients taking this medicine. Adverse effects may differ from patient to patient. Here is the list of adverse effects of this drug.

  • Dry mouth
  • Insomnia
  • Dizziness
  • Fatigue
  • Nausea
  • Pharyngitis
  • Dyspepsia
  • Anorexia
  • Back pain
  • Blurred vision
  • Chest pain
  • Ear pain
  • Conjunctivitis
  • Flu-like symptoms
  • Tinnitus
  • Weight gain

Please contact your doctor if you are experiencing any of the side effects. If you have bought this medicine over the counter, stop taking this medicine and contact your health care provider for alternative medication.

Effects on organs

Cardiovascular system:  Claritin D causes following cardiac problems- Hypertension, palpitations, syncope, tachycardia, peripheral edema.

Pseudoephedrine in the drug which can elevate blood pressure. Hence this drug is not advised for patients with uncontrolled blood pressure.

Respiratory: It can cause chest congestion, dry throat, dyspnoea, bronchitis, irritation, wheezing, etc.

Gastrointestinal: Abdominal pain, distension, constipation, flatulence, gastritis. The frequency of these effects is not reported and these effects may be rare.

Nervous system: Hallucinations, restlessness, tremors, insomnia, anxiety, headache and tremors.

Urinary: Retention of the urine can occur which is rare.

Warnings and Precautions if any

  • Claritin D 24-hour tablet should be used in caution with patients having trouble in swallowing, upper GI narrowing, and abnormal peristalsis. Studies have shown the occurrence of eosophageal obstruction and perforation. Do not use this tablet unless prescribed by your doctor, if you are suffering from the above condition.
  • Patients with cardiac problems, Thyroid problems, Kidney problems, Prostate diseases, or generalized conditions like diabetes and hypertension should not take them over the counter. Please consult your physician before taking this medicine.

Reported Allergic Reactions

Skin rashes can occur with drug eruption in the form of red patches, which is very rare. Please let your doctor know if you are allergic to any medicines for allergy and the common cold, other allergic conditions like urticaria, pruritis, etc.

Effect of the Medicine on the Menstrual Cycle

No, significant effects on menstrual cycles are not reported.

Drug Interactions to Be Careful About

  • Erthromycin
  • Ketoconazole
  • Cimetidine
  • Pseudoephedrine is contraindicated in patients who are taking MAO Inhibitors for the past 14 days.
  • Methyldopa, Mecamylamine, Reserpine, Veratrum alkaloids. The efficacy of these drugs is reduced by Claritin D.
  • When used along with Digitalis, increased ectopic pacemaker activity is observed.

However, these drug interactions are for informative purposes only. Your doctor might suggest an alternative medicine or adjust the dosage according to your condition. If you are taking any treatment for other health conditions, it’s suggestive not to take Claritin D over the counter. Before taking the medicine, consult your healthcare provider.

Food interactions

No specific food interactions reported. If you are allergic to any foods or drugs, let your doctor know so that he might suggest changes in your treatment plan.

Interactions with laboratory procedures

In vitro studies showed that the pseudoephedrine present in this medicine inhibits the action of serum creatinine phosphokinase. There are no clear pieces of evidence about laboratory interactions of this drug.

Shows Effects / Results in (How Long Does the Effect Stay?)

It shows effects in 3-4 hours after the consumption and its efficacy stays for 10 to 12 hours.

Is CLARITIN D Addictive?

Loratadine in medicine is not addictive. Pseudoephedrine component can be addictive. Using high doses of Claritin D can cause mood elevation, increased sense of alertness and increased energy. On withdrawal, depression may follow.

Can I have CLARITIN D with alcohol?

 The antihistamine in this drug is not drowsiness causing type. Some people may experience dizziness after taking this drug due to various reasons. So avoid drinking alcohol or operating heavy tools/machinery until the course is over.

Can I have CLARITIN D When Pregnant?

Claritin D should not be used during pregnancy unless the benefits outweigh the risks and only when prescribed by your doctor.

Can I have CLARITIN D when feeding a baby?

Studies have shown that it is excreted into human milk.  Please contact your doctor before taking this medication during breast feeding.

Pseudoephedrine in this medicine may cause a decrease in lactation in mothers who are not able to produce sufficient milk.

Can I drive after taking CLARITIN D?

This drug may cause drowsiness and blurred vision. Hence it is suggested not to drive or operate heavy machinery after taking this medicine.

Effect of an overdose of CLARITIN D

The large doses of Claritin D may cause giddiness, vomiting, tachycardia, insomnia, muscle weakness, convulsions, cardiac arrhythmias, collapse, and respiratory failure. Please contact your doctor immediately if you have taken excess doses of Claritin D.

Effect of using expired CLARITIN D

Expired Claritin D may not show intended benefits. Dispose of the medicines according to the guidelines. If you are buying it over the counter, please check the expiry date before purchasing it.

Effect of missing a dose of CLARITIN D

Missing a single dose may not show much effect. If you are skipping doses frequently it may not show benefits intended. Since it is taken 12 hourly or 24 hourly, set a reminder until the course is finished or take the medicine daily at the same time. Take the missed dose immediately when you remember, if it is not close to the next dose.

Storage requirements

  • This medicine should be kept under room temperature
  • Keep them away from the reach of children and pets.
  • Keep it away from moisture.

Substitutes for CLARITIN D

  • Claritin
  • Nasacort Aq
  • Zyrtec D
  • Afrinol
  • Allermed
  • Cenafed
  • Contac Cold

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