Bromhexine – Composition, Uses, Side-Effects, Substitutes, Warnings

Bromhexine is a mucolytic drug and belongs to an over the counter medication that supports the body’s mechanism for clearing mucus from the respiratory tract. It is used especially to treat the respiratory disorders associated with viscid or excessive mucus. Get to know how Bromhexine works, its side effects and precautions.

Read about similar medications

It also has antioxidant properties. Bromhexine is a synthetic derivative of the herbal active ingredient vasicine. It belongs to a group of medication called Mucolytics. Bromhexine is manufactured by Densa Pharma.

Composition of Bromhexine

Bromhexine consists of Bromhexine HCl as an active ingredient. The drug is a Benzylamine derivative of-

  • 2 amino-3,5-dibromo-N-cyclohexyl N- Methylbenzylamine hydrochloride
  • The other alkaloids taken from the plant of adhatodavasica

Mechanism of action of Bromhexine

Bromhexine increases sputum volume and decreases the thickened bronchial secretions in chronic bronchitis patient, when it is administered orally.

It stimulates the activity of ciliated epithelium. Bromhexine also increases lysosomal activity, hence the improvement of pulmonary function in bronchitis patients.

Indication and benefits of Bromhexine

It is prescribed for the following list of treatment, control, prevention of the diseases, symptoms, and conditions:

  • Chest congestion and cough
  • Acute and chronic Broncho pulmonary disease
  • Breathing difficulty
  • Sinusitis

Dosage of Bromhexine

Bromhexine dosage depends on your age, your health condition, severity of the disease and other medications that you are currently taking.

The drug is available in tablet and liquid form. The tablets are usually taken 3 times per day, along with plenty of fluids and after meals. The syrup can be given 2 to 4 times per day.

Side effects of Bromhexine

Some side effects may be seen by active ingredients of Bromhexine. Below listed side effects may be possible, but may not necessarily occur. Following side effects are rare but life-threatening. Please visit your doctor if you observe any of the following side effects.

The following are the side effects of Bromhexine

  • Nausea
  • Skin rash
  • Vomiting
  • Diarrhea
  • Pain in the upper part of stomach
  • Urticaria
  • Dizziness and headache
  • Nocturnal enuresis

Bromhexine – Precautions and How to use

  1. Inform your doctor, before you use Bromhexine, about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, present and past health status, pregnancy, upcoming surgeries.
  2. Some of the health condition can make the body more susceptible to the side-effects of the drug
  3. Take as exactly prescribed by your doctor or follow the direction printed on the product insert.
  4. Dosage always depends upon your condition.
  5. Do not take this medicine after the expiry date stated on the medicine.
  6. Store the medicine away from reach of children.
  7. Use the full course of treatment.
  8. Bromexine can be stored at room temperature. Avoid direct exposure to heat and sunlight.
  9. Visit or consult immediately with the doctor while taking the drug if your condition persists or worsens.

Important conselling points are

  • Patient should be notified of an increase in the flow of secretions.
  • If the symptoms do not subside until 14 days of usage, please consult your doctor.
  • The drug should be taken under medical supervision.
  • The effect of the drug may be reduced in patients with severe hepatic or renal impairment.
  • Caution should be taken if advised to asthmatic patients.

Missed Dose

A missed dose should be taken as soon as you remember. If it is near time for next dose, you can skip the previous dose but never take a double dose.


If you have taken extra dose of Bromhexine visit or consult your doctor immediately. In case of overdose, supportive and symptomatic treatment should be provided.

Bromhexine contraindications

Hypersensitivity to Bromhexine drug is a contraindication. Bromhexine drug is also contraindicated if you have the following symptoms or conditions:

  • Impaired kidney function
  • Allergic reactions
  • Liver disease
  • Hypersensitivity

Bromhexine Drug interactions

If you take the other medications or over the counter products at the same time, the effect of Bromhexine drug may change.  It can increase chances of side effects or make your drug work improperly.  Inform your doctor about your complete health history so that it becomes easier to manage or prevent drug interactions.

The drug interactions of Bromhexine are:

  • Nutritional supplements
  • Herbal products

Substitutes of Bromhexine

  • Bisolvon
  • Bisolpent
  • Solvex
  • Bisolex
  • Brufentol
  • Mucolyte
  • Ambroxol

If for some reason an experienced doctor is not available around you, then you can contact us here.


    Bromhexine - Composition, Uses, Side-Effects, Substitutes, Warnings
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