Table of Contents

  1. What is Belbien?
  2. Belbien composition
  3. History behind the Belbien
  4. Belbien Indications
  5. How does Belbien work? (Belbien Mechanism of Action)
  6. How to Take Belbien?
  7. Common Belbien Dose
  8. When to Avoid Belbien?
  9. Belbien Side Effects
  10. Effects on organs
  11. Warnings and Precautions
  12. Reported Allergic Reactions
  13. Effect of Belbien on the menstrual cycle
  14. Drug Interactions To Be Careful About
  15. Food interactions of Belbien
  16. Interactions with laboratory procedures
  17. How Long Does the Effect Stay?
  18. Is Belbien Addictive?
  19. Can I have Belbien with alcohol?
  20. Can I have Belbien When Pregnant?
  21. Can I have Belbien when feeding a baby?
  22. Can I drive after taking Belbien?
  23. Effect of an overdose of Belbien
  24. Effect of using expired Belbien
  25. Effect of missing a dose of Belbien
  26. Storage requirements
  27. Substitutes for Belbien

What is Belbien?

Belbien is a prescription medicine used to treat insomnia as a short term treatment option and is known to available in Serbia. Let’s explore more details about the medication and its side effects, precautions, etc.

Belbien composition

Belbien is composed of Zolpidem as an active ingredient and may be available in Serbia, manufactured by HemoFarm Pharma.

History behind the Belbien

Zolpidem is the main ingredient in the medicine, which was initially approved for medical use in 1992. The generic version of it started in 2007. Zolpidem is under scheduled IV controlled drug under the Controlled Substances Act of 1970.

Belbien Indications

Belbien is prescribed to treat insomnia. It is also called as a sedative or hypnotic medicine. 

How does Belbien work? (Belbien Mechanism of Action)

Belbien works by acting on certain imbalanced chemicals in the brain that is causing insomnia in the patients. It works by increasing the GABA effect in the CNS (Central Nervous System). This medicine is available in two variations like immediate-release tablets and extended release tablets. First versions dissolve immediately and make you fall asleep immediately. The second version has two layers, the outer layer dissolves first to make you fall asleep and the inner layer dissolves slowly and helps to stay asleep.

How to Take Belbien?

Belbien is available in tablets form and is used as any other medicine with a glass of water. It is used once a day preferably before bedtime where you have at least 7 to 8 hours to sleep.

Common Belbien Dose

Commonly recommended doses are –

  • Women – 5mg
  • Men – 5mg to 10 mg

In case of extended release version, the dosage is like –

  • Women – 6.25mg
  • Men – 6.25mg to 12.5 mg

Details mentioned here are for information only and shall not be taken as medical advice.

When to Avoid Belbien?

Belbien is advised to avoid in some conditions and patients suffering some health issues like mentioned below.

  • In patients with depression, hallucinations, drug abuse, myasthenia gravis, suicidal thoughts
  • In patients with health issues like severe COPD, severe liver disease,
  • While traveling when you don’t have enough time (7-8 hours) to sleep
  • Not advised to use in patients below 18 years of age

Belbien Side Effects

Belbien may cause side effects in some patients. Dizziness and drowsiness are the most common side effects reported. May also cause some more side effects like –

  • Myalgia
  • Anxiety
  • Hallucination
  • Nausea

This is not a comprehensive list of side effects and is advised to consult your doctor immediately if any side effects are seen.

Effects on organs

Belbien may cause issues related to some organs and functional systems in the body. For example –

  • Metabolic – Anorexia, and appetite disorder
  • Cardiovascular – Increased blood pressure, and palpitations
  • Immunologic – Infection, influenza, and influenza-like symptoms
  • Dermatologic – Rash, skin wrinkling, urticarial
  • Genitourinary – Dysuria, menorrhagia, urinary tract infection, and vulvovaginal dryness
  • Musculoskeletal – Arthralgia, back pain, muscle cramp, myalgia, neck pain
  • Ocular – Abnormal vision, altered visual depth perception, asthenopia, blurred vision, diplopia, eye redness, and visual disturbance
  • Respiratory – Hiccup, lower respiratory infection, upper respiratory infection, nasopharyngitis, pharyngitis, rhinitis, sinusitis, throat irritation
  • Nervous system – Dizziness, headache, and somnolence
  • Gastrointestinal – Abdominal discomfort, abdominal pain, and constipation

Warnings and Precautions

As a precaution, it is advised to share the general details about your health with your doctor before prescription to avoid complications. Inform your doctor if you have any history of the below-mentioned symptoms or issues.

  • Depression
  • Mental Illness
  • Suicidal Thoughts
  • Drug or Alcohol Addiction
  • Lung Disease / Breathing Problems
  • Sleep Apnea
  • Liver or Kidney Disease

Reported Allergic Reactions

Belbien may cause allergic reactions in some patients. Symptoms of allergic reactions include as mentioned below. It is advised to stop the usage and consult the doctor immediately if any such allergic symptoms are seen.

  • Hives
  • Difficulty Breathing
  • Swelling of Facial Organs, Tongue, or Throat

Effect of Belbien on the menstrual cycle

Belbien may cause irregular or prolonged menstrual cycles. Consult your doctor if you see such changes in cycles while using this medicine.

Drug Interactions to Be Careful About

Belbien may show drug interactions if used at the same time with some other medicine. Below mentioned are some medicine that Belbien my show drug interactions.

  • Hydrocodone
  • Acetaminophen
  • Oxycodone
  • Buprenorphine
  • Naloxone
  • Tramadol
  • Xanax (Alprazolam)

Food interactions of Belbien

There are no specific foods mentioned to avoid. But it is suggested not to take the medicine along with the food or immediately after eating food as it would delay the onset of action of the medicine.

Interactions with laboratory procedures

Limited data is available on the interaction of Belbien with laboratory procedures. As a general precaution, let your doctor know about your current prescription of Belbien if you are about to attend any diagnostics.

How Long Does the Effect Stay?

Belbien starts to work approximately 45 minutes with its peak effect in 1.6 hours. The medicine is metabolized in the liver and the estimated elimination half-life is 2.6 hours.

Is Belbien Addictive?

Belbien can be addictive in some patients who already have the risk of drug addiction or alcohol addiction.

Can I have Belbien with alcohol?

Not advised to take the Belbien along with alcohol or after few hours of consuming the alcohol. It can cause increased dizziness and lead to serious side effects like shallow breathing coma or even death. 

Can I have Belbien When Pregnant?

Not advised to use in pregnancy especially in the final 3 months of pregnancy as it can cause drowsiness and breathing problems in newborns.

Can I have Belbien when feeding a baby?

Not advised to use in general as the medicine can pass into the mother’s milk and an effect on the infant.

Can I drive after taking Belbien?

No, not advised to do activities like driving etc. after using the Belbien as it causes dizziness.

Effect of an overdose of Belbien

Never overdose the medicine as it can be more fatal and result in serious side effects like mentioned below. Seek immediate medical advice if any such symptoms of overdose occur.

  • Excess sleepiness
  • Confusion
  • Shallow breathing
  • Light-headed
  • Fainting
  • Coma

Effect of using expired Belbien

An expired medicine may not give the benefits that it is supposed to give. FDA also insists to avoid any medicine that is expired. As a precaution check the manufactured and expiry dates on the label while purchasing any medicine.

Effect of missing a dose of Belbien

There is the least possibility of missing a dose of Belbien as it is used only once in a day before going to bed. But nor harm would happen if you miss a dose but you tend to miss the doses regularly, try setting a reminder.

Storage requirements

Advised to store at room temperature away from direct sunlight and heat. Never freeze this medicine. Store it out of reach to children or pets.

Substitutes for Belbien

Below mentioned are some available brands of Belbien and may be prescribed by your doctor as an alternative to treat insomnia as a short term treatment.

  • Ambien
  • Ambien CR
  • Intermezzo
  • Edluar
  • Zolpimist



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