Baclofen is an Anti-spastic, anxiolytic agent which is used to relieve pain and improves the muscle movement. Baclofen is used to treat muscle symptoms caused by multiple sclerosis, including spasm, pain, and stiffness. This drug sometimes used to treat muscle spasm and other symptoms in people with injury or disease of the spinal cord.

How does Baclofen work?

Baclofen is a type of drug known as a GABA (gamma amino butyric acid) receptor agonist. This means that it reduces the transmission of messages between nerve cells and decreases the muscles contraction and stiffness.

Indications and Usage for Baclofen

Baclofen is used in the treatment of spasticity (muscle stiffness) caused due to the brain or spinal cord injury characterized by stiffness of muscles and interferes with normal body movement.

Baclofen tablets are useful for the alleviation of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of muscular rigidity, flexor spasms and concomitant pain, and clonus.

Baclofen tablet may also be of some value in patients with spinal cord injuries and other spinal cord disorders. Patients should have reversible spasticity so that baclofen treatment will aid in restoring residual activities.

Baclofen not recommended in the treatment of skeletal muscle spasm resulting from rheumatic diseases. The effect of baclofen tablet in Parkinson’s disease, stroke, and cerebral palsy has not been established and, therefore, it is not advised for these conditions.

Side effects of baclofen

In addition to its intended effect, even though it may be rare, some people may have very bad and sometimes deadly side effects when taking Baclofen. You must seek medical attention immediately if you notice following signs or symptoms:

  • Dizziness
  • Nausea or Vomiting
  • Ringing or buzzing in the ears
  • Skin rash
  • Confusion
  • Change in mood
  • Constipation
  • Difficult or painful urination
  • Muscle weakness
  • Headache

Baclofen tablet contraindicated in following conditions:


Avoid if you have allergy to Baclofen tablet or other NSAIDs


Baclofen tablet is contraindicated if you are diagnosed with asthma or other respiratory complications.


If you are suffering from any bleeding disorder Baclofen tablet is not recommended for you. It could cause severe swelling and bleed in the intestines, stomach, and anus.

Liver Disease

Baclofen tablet should be used with extreme caution in patients suffering from liver disease due to the increased risk of severe adverse effects.

Peptic Ulcer

Baclofen is not recommended if you have peptic ulcer or are suspected of having it. It could cause severe swelling and bleeding in the stomach, colon, and anus.

 Coronary Artery Bypass Surgery (CABG)

Baclofen tablet is not recommended for relieving pain after you have undergone Coronary Artery Bypass Surgery.

Doctor’s advice for Baclofen Tablet:

  • Baclofen is a very safe and well-tolerated medicine for short-term use
  • Consuming high dose or taking long time Baclofen can cause kidney problems and stomach bleeding
  • If you are suffering from kidney disease, inform your doctor first. Your dose may need to be adjusted
  • When you taking Baclofen tablet, Avoid excess intake of alcohol, together they can affect your liver
  • If you have taken overdoses of Baclofen Immediately inform your doctor or contact a hospital emergency and you are feeling unwell
  • Avoid taking alcohol or salicylates to prevent bleeding
  • Inform your doctor if you have bruising or bleeding
  • Consult your doctor if you have systemic lupus erythematosus
  • Consult your doctor if you develop blurred vision, ringing or roaring in ears
  • Take the drug with a meal or snack to prevent upset stomach

Baclofen Tablet – Precautions & How to Use

Some medications are not suitable for people with certain ailments, and sometimes a medicine may only be used if extra care is taken. Take this medicine as directed by your doctor or follow the direction printed on the product insert. Tell your doctor if your condition persists or worsens. Dosage is based on your condition. Do not give the medication to a child younger than Two years old without the advice of a doctor. Before taking Baclofen, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. Baclofen may contain inactive ingredients, which can cause allergic reactions or other problems.

  • Avoid using it if allergic to paracetamol
  • Avoid exposing medication to excessive heat
  • Do not take paracetamol if you consume alcoholic beverages every day
  • Consume the medicine only at recommended doses

Baclofen Dosage

Baclofen tablet comes in 10 & 20 mg (milligrams), and you’ll usually take an equally divided dose three times a day. These tablets have a score mark, which is an indented line down the middle, so you can cut them in half if required.

Your doctor may start you at a small dose and then gradually increase it. The goal is to take the lowest effective dose.

Baclofen dose schedule is:

  • 5 mg 3 times a day for the first 3 days
  • 10 mg 3 times a day for the next 3 days
  • 15 mg 3 times a day for the next 3 days
  • 20 mg 3 times a day for the next 3 days

It may take a few weeks for the drug to reach the peak effectiveness.

The usual daily dose is 40 to 80 mg (milligrams). The higher dose should not be higher than 80 mg a day.

General warnings:


Taking more than prescribed Baclofen may cause harmful side effects. Consult your doctor or pharmacist if you find any side effects.

Missing dosage

If you miss the dosage take as soon as possible, and if it is near to next dose, skip the missing dosage continue the regular dosage. Do not take extra doses.


Baclofen is not recommended for use in pregnant women unless necessary and the potential benefits outweigh the risks involved. Baclofen is not known to cause any harm to the fetus, but should only be used after consultation with your doctor.


Baclofen is safe to use during breastfeeding. Before taking this medicine consult your doctor.

Substitutes for Baclofen

Below is the list of drugs, which have the same composition, strength and form as Baclofen, and hence can be used as its substitute:

  • Arive 10 MG Tablet–Alkem Laboratories Ltd
  • Bizlo 10 MG Tablet–Unichem Laboratories Ltd
  • Baclotop 10 MG Tablet–Zuventus Healthcare Ltd
  • Lobaset 10 MG Tablet–Emcure Pharmaceuticals Ltd

Spinobak 10 MG Tablet–Mankind Pharmaceuticals Ltd

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